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Do Artificial Sweeteners Cause Hormonal Disruption?

 

Medical Reviewed By Lucas Rosa

PhD in Molecular Biology

 

 

Artificial sweeteners could be dangerous for our hormones because of the potential hormonal disruption that they could be causing.

 

The Rise of Artificial Sweeteners

Artificial sweeteners have gained significant popularity over the past few decades as a sugar substitute. Originally marketed as a way to reduce caloric intake and fight obesity, these sweeteners are now found in a wide range of products, from diet sodas to sugar-free snacks.

While they offer sweetness without calories, concerns have been raised about the long-term health effects of artificial sweeteners. Some studies suggest that the trade-offs might not be as beneficial as initially thought.

Further research is needed to fully understand the long-term health effects of artificial sweeteners, but they may not be the healthy alternatives to sugar that many hope for. It is important to note that artificial sweeteners are generally considered safe to consume by government health agencies.

 

Possible Health Effects of Insulin Imbalance (6)-1

 

Common Artificial Sweeteners

These are common artificial sweeteners that are added to foods and beverages.

  • Acesulfame potassium (Ace-K) - 180 times sweeter than table sugar
  • Advantame - 20,000 times sweeter than table sugar
  • Aspartame - 200 times sweeter than table sugar
  • Neotame - 7,000 times sweeter than table sugar
  • Saccharin - 200 times sweeter than table sugar
  • Sucralose - 600 times sweeter than table sugar

Most artificial sweeteners are made in labs and do not contain any nutrients in them. Consistent consumption of artificial sweeteners can easily get your tastebuds accustomed to sweetness since they are hundreds of times sweeter than table sugar.

 

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Artificial Sweeteners & Hormonal Disruption

The endocrine system is a network of glands that produce and release hormones, which play a crucial role in regulating various bodily functions. Hormonal balance is essential for our overall well-being, and artificial sweeteners could possibly be interfering with this delicate balance in multiple ways.

Research has suggested that artificial sweeteners may influence the hormones involved in appetite regulation. Some artificial sweeteners have been found to mimic the structure of natural hormones by binding to sweet taste receptors, potentially leading to disruptions in hormones.

For example, some studies have shown that artificial sweeteners can have an impact on insulin sensitivity which is a key factor in regulating blood sugar levels. While other studies have suggested that artificial sweeteners have little or no impact on insulin.

Other artificial sweeteners may affect gut bacteria, which in turn can influence hormone production and regulation. But similar to its potential effect on insulin, the results from studies are conflicting. 

The findings are not very conclusive, but they all raise questions about the long-term safety of consuming artificial sweeteners, especially for individuals who use them regularly.

 

Ways To Counteract Insulin Resistance (2)

 

Natural Alternatives To Artificial Sweeteners

If you're concerned about the potential hormonal impacts of artificial sweeteners, there are natural alternatives that you can consider.

Natural Sweetener Alternatives:

  • Stevia - made from stevia leaves and 200 times sweeter than table sugar
  • Monk Fruit Extract - made from monk fruit and 200 times sweeter than table sugar
  • Honey - made from bees and is 1.25 times sweeter than table sugar
  • Coconut Sugar - made from coconuts and has similar sweetness to table sugar
  • Molasses - made from sugar cane or sugar beets and is less sweet than table sugar
  • Yacon Syrup - made from the yacon plant and less sweet than table sugar
  • Maple Syrup - made from maple trees and is less sweet than sugar

Additionally, these sweeteners not only provide a natural way to satisfy your sweet tooth but also come with additional nutrients that can support overall well-being.

Always remember to use sweeteners in moderation and maintain a balanced diet. Consult with healthcare professionals to tailor your dietary choices to your specific health needs.

 

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Conclusion

While artificial sweeteners offer a calorie-free way to enjoy sweetness, there potentially could be long-term health effects of using them. Research is conflicting in this area, but there is some research suggesting that artificial sweeteners affect our hormones.

By being mindful of your body's responses to sweeteners, you can enjoy the benefits of sweetness without compromising your hormonal balance.

 


 

Sources:

Azad, Meghan B., et al. “Nonnutritive Sweeteners and Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies.” Canadian Medical Association Journal, vol. 189, no. 28, 16 July 2017, pp. E929–E939, www.cmaj.ca/content/189/28/E929https://doi.org/10.1503/cmaj.161390

Begum, Jabeen. “What Is Stevia?” WebMD, 21 Sept. 2022, www.webmd.com/food-recipes/what-is-stevia

Cook, Emily. “Why Artificial Sweeteners Can Increase Appetite.” The University of Sydney, 13 July 2016, www.sydney.edu.au/news-opinion/news/2016/07/13/why-artificial-sweeteners-can-increase-appetite.html

Holman, Tayla. “The Not-So-Sweet Effects of Artificial Sweeteners on the Body.” HCA Florida Healthcare, 3 June 2024, www.hcafloridahealthcare.com/healthy-living/blog/the-not-so-sweet-effects-of-artificial-sweeteners-on-the-body

Mathur, Kushagra, et al. “Effect of Artificial Sweeteners on Insulin Resistance among Type-2 Diabetes Mellitus Patients.” Journal of Family Medicine and Primary Care, vol. 9, no. 1, 28 Jan. 2020, pp. 69–71, www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/, https://doi.org/10.4103/jfmpc.jfmpc_329_19

Mayo Clinic Staff. “Pros and Cons of Artificial Sweeteners.” Mayo Clinic, 8 Oct. 2020, www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/artificial-sweeteners/art-20046936

Persellin, Ketura. “Surprise! Some of Your Favorite Foods May Contain Artificial Sweetener | Environmental Working Group.” Environmental Working Group, 27 Nov. 2023, www.ewg.org/news-insights/news/2023/11/surprise-some-your-favorite-foods-may-contain-artificial-sweetener

Ruiz-Ojeda, Francisco Javier, et al. “Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials.” Advances in Nutrition, vol. 10, no. suppl_1, 1 Jan. 2019, pp. S31–S48, www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/, https://doi.org/10.1093/advances/nmy037

Swithers, Susan E. “Artificial Sweeteners Produce the Counterintuitive Effect of Inducing Metabolic Derangements.” Trends in Endocrinology & Metabolism, vol. 24, no. 9, Sept. 2013, pp. 431–441, https://pmc.ncbi.nlm.nih.gov/articles/PMC3772345/#S18, https://doi.org/10.1016/j.tem.2013.05.005.

The Cleveland Clinic. “Is Monk Fruit a Healthy Sweetener?” Cleveland Clinic, 5 Aug. 2021, https://health.clevelandclinic.org/why-you-should-use-monk-fruit-sweetener

U.S. Food and Drug Administration. Aspartame and Other Sweeteners in Food. 14 July 2023, www.fda.gov/food/food-additives-petitions/aspartame-and-other-sweeteners-food

Ziesel, Jessica. “Facts about Sugar and Sugar Substitutes.” Johns Hopkins Medicine, 2022, www.hopkinsmedicine.org/health/wellness-and-prevention/facts-about-sugar-and-sugar-substitutes

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